High molecular weight cytokeratins
WebTo overcome the difficulties in the biochemical analysis of highly cross-linked polymers and aggregates of cytokeratins, cross-linked cytokeratin dimers were analyzed by immunoblotting to evaluate the degree of cross-linking of cytokeratins. ... However, cytokeratin dimers and high-molecular-weight cytokeratin polymers were detected in liver ... WebIn general, most low molecular weight cytokeratins (40-54 kDa) are distributed in nonsquamous epithelium, Monoclonal mouse anti-human cytokeratin, High Molecular Weight (HMW), clone 34BE12 (anti-CK, HMW, 34BE12) is to identify the 66, 57, 51 and 49 kDa1 proteins corresponding to cytokeratins 1, 5, 10 and 14 of the Moll catalog, in normal …
High molecular weight cytokeratins
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WebSep 8, 2014 · Abstract. The tissue expression of low (LMW) and high (HMW) molecular weight cytokeratins and Ber-EP4 antigen in both small (SCLC) and non-small (NSCLC) cell … http://qcmark.org/epitopes/cytokeratin/
WebNov 1, 2000 · Our data show that the high-molecular-weight cytokeratin antibody 34βE12 is an insensitive but ... Zarbo RJ, Bacchi CE, Gown AM . Coordinate expression of cytokeratins 7 and 20 defines unique ... WebNov 16, 2024 · Along with polyclonal cytokeratins such as AE1/AE3 and high molecular weight cytokeratin antibodies (34betaE12, Cam 5.2), epithelial membrane antigen (EMA) and vimentin, they are included in every diagnostic panel for renal tumors.
WebNov 1, 2002 · The anti-cytokeratin antibody, 34βE12, which corresponds to keratin 903, is specific for high molecular weight cytokeratins (cytokeratin 1, 5, 10, and 14) as catalogued by Moll et al. ( 1 ). WebImmunohistochemical expression of myoepithelial markers in adenomyoepithelioma of the breast：a unique paradoxical staining pattern of high-molecular weight cytokeratins [J]. Virchows Arch ， 2015 ， 466 ( 2 ): 191 - 198 .
WebHematoxylin and eosin (H&E) staining is a well-established technique in histopathology. However, immunohistochemistry (IHC) interpretation is done exclusively with hematoxylin counterstaining. Our goal was to investigate the potential of H&E
WebDec 1, 2000 · The antigenicity of high-molecular-weight cytokeratins could be restored using microwave retrieval in an acidic buffer. Although the exact mechanism concerning microwave antigen retrieval is not clear, it is possible that this technique restores antigenicity by unfolding of keratin or an interacting protein.13 Recently, ... reactive attitudes defineWeb34βE12. 34βE12, often written as 34betaE12 and also known as CK34βE12 and keratin 903 ( CK903 ), is an antibody specific for high molecular weight cytokeratins 1, 5, 10 and 14. [1] [2] It is sometimes, less precisely, referred to as high-molecular weight keratin ( HMWK) and high-molecular weight cytokeratin ( HMWCK ). reactive atypiaThere are two categories of cytokeratins: the acidic type I cytokeratins and the basic or neutral type II cytokeratins. Within each category, cytokeratins are numbered in order of decreasing size, from high molecular weight (HMWCKs) to low molecular weight (LMWCKs). Cytokeratins are usually found in … See more Cytokeratins are keratin proteins found in the intracytoplasmic cytoskeleton of epithelial tissue. They are an important component of intermediate filaments, which help cells resist mechanical stress. Expression of these … See more The term cytokeratin began to be used in the late 1970s, when the protein subunits of keratin intermediate filaments inside cells were first being identified and characterized. In … See more In the cytoplasm, keratin filaments associate laterally with each other to create bundles of ~50 nm radius. The radius of these bundles is set by the interplay between long range electrostatic repulsion and short range hydrophobic attraction. These … See more The cytokeratins are encoded by a family encompassing 30 genes. Among them, 20 are epithelial genes and the remaining 10 are specific for … See more • Cytokeratin at the U.S. National Library of Medicine Medical Subject Headings (MeSH) See more reactive atypia favoredWebThe cytokeratins are the largest and most complex group of intermediate filaments and include a family of at least 30 proteins with molecular weights ranging from 40 to 68 kD. … reactive atypia cervixWebHigh molecular weight cytokeratin. Good basal cell marker. Stains basaloid squamous carcinomas, basal-like type ductal carcinoma (aka - triple negative ductal carcinoma), and … reactive atypia esophagusWebMay 5, 2005 · It was recognized by many groups that the high-molecular-weight cytokeratins CK5 and CK14, which form in vivo complexes, are expressed in the basal … reactive atypia meaningWebThe distribution of tissue polypeptide antigen (40 kD molecular weight) in normal adult and fetal liver, and in liver disease was investigated and compared with the distribution of low and high molecular weight cytokeratins. In normal liver tissue polypeptide antigen was found only in bile duct epithelium; this distribution is similar to that of high molecular … reactive atypia icd 10