Dab2 interacting protein
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Dab2 interacting protein
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WebDOC-2/DAB2 interacting protein (DAB2IP) is a RasGAP protein that shows a suppressive effect on cancer progression. Our previous study showed the involvement of transcription regulation of DAB2IP in metastasis of colorectal cancer (CRC). However, the molecular mechanisms of DAB2IP in regulating the progression of CRC need to be further explored. WebSep 17, 2024 · Meanwhile, the DOC-2/DAB2 interacting protein DAB2IP was previously identified as a member of the Ras-GTPase activating protein family, and functions as a tumor suppressor in cancer progression 7,8.
WebMar 21, 2024 · DAB2 (DAB Adaptor Protein 2) is a Protein Coding gene. Diseases associated with DAB2 include Teratocarcinoma and Hypercholesterolemia, Familial, 4 . … WebSep 26, 2024 · Orthologous to human DAB2IP (DAB2 interacting protein). [provided by Alliance of Genome Resources, Apr 2024] Other designations. disabled homolog 2-interacting protein, ASK-interacting protein 1, ASK1-interacting protein 1, DAB2-interacting protein, DOC-2/DAB-2 interactive protein, disabled 2 interacting protein …
WebDescription: Homo sapiens DAB2 interacting protein (DAB2IP), transcript variant 1, mRNA. (from RefSeq NM_032552) RefSeq Summary (NM_032552): DAB2IP is a Ras (MIM 190020) GTPase-activating protein (GAP) that acts as a tumor suppressor. The DAB2IP gene is inactivated by methylation in prostate and breast cancers (Yano et al., 2005 … Disabled homolog 2-interacting protein is a protein that in humans is encoded by the DAB2IP gene. DAB2IP is a Ras (MIM 190020) GTPase-activating protein (GAP) that acts as a tumor suppressor gene and is inactivated by methylation in prostate and breast cancers (Yano et al., 2005).[supplied by OMIM]
WebNov 18, 2016 · The cytoplasmic Ras-GAP protein DAB2IP (Disabled-2 Interacting Protein) is a negative modulator of multiple oncogenic pathways. DAB2IP is rarely mutated, but frequently downregulated or ...
WebJun 16, 2003 · Identification of Dvl-3 as a Dab2-interacting protein. (A) Schematic representation of the small-pool cDNA screening strategy using GST–PID.(B) Schematic representation of the domain structure of Dvl … milwaukee glue gun cordlessWebASK1-interacting protein-1 (AIP1) is a newly discovered signal scaffold protein, which is a member of the Ras-GTPase activating protein (Ras-GAP) family. 8 The expression of AIP1 in tumor cells is inhibited by histone-lysine N-methyltransferase EZH2 protein, 9,10 which is highly expressed in various tumor tissues and functions to promote the ... milwaukee gov cityWebJan 1, 2024 · Related articles in PubMed ASK1-Interacting Protein 1 Acts as a Novel Predictor of Type 2 Diabetes. Song Z, et al. Front Endocrinol (Lausanne),... DAB2IP … milwaukee golf expoWebJan 1, 2024 · DAB2IP, DAB2 Interacting Protein; KIF3a, kinesin family member 3A; RCC, renal cell carcinoma; TCGA, The Cancer Genome Atlas. Discussion. Primary cilium is a microtubule-based structure that protrudes from the centrosomal mother centriole (also known as basal body) into the extracellular milieu [30]. Since cilium axoneme is … milwaukee government officesWebSep 1, 2024 · DAB2 interacting protein (DAB2IP) was screened as a direct target of miR-1307-3p. The expression of DAB2IP. mRNA was down-regulated and inversely correlated with miR-1307-3p level in HCC tissues ... milwaukee.gov click for actionWebOct 18, 2024 · Some GAPs can promote apoptosis of tumor cells to protect the organism. p120RasGAP, regulator of G-protein signaling 3 (RGS3), deleted in liver cancer 1 (DLC1), DOC-2/DAB2 interacting protein (DAB2IP), and STARD13 are typical examples because the five GAPs can influence the balance of antiapoptotic proteins and proapoptotic … milwaukee gov treasurerWebClinVar archives and aggregates information about relationships among variation and human health. milwaukee grass trimmer and blower combo