WebMar 17, 2024 · Combining multiple ML and cytohubba algorithms yielded 11 relevant genes. ... EPC, EcCentricity, Radiality, Closeness and Betweenness algorithms were used to calculate the associated gene scores (Supplementary Figure S2A–G). The UpSet graph was used to filter out five common HF-associated genes ... WebAmong the 11 topology analysis methods included in cytoHubba, Botteleneck and Radiality (Chin et al., 2014) were chosen as the main topological analysis methods for scoring and …
Identification of hub genes and transcription factors in
WebMar 4, 2024 · A plugin named cytoHubba was introduced to screen hub genes of PPI network in Cytoscape. CytoHubba can provide 12 topological analysis methods including Betweenness, BottleNeck, Closeness, Clustering Coefficient, Degree, DMNC, EcCentricity, EPC, MCC, MNC, Radiality and Stress based on shortest paths . Results. Normalization … WebDownload scientific diagram Hub genes analysis during heart maturation: (A) Upset analysis demonstrates hub genes analyzed in Cytoscape plug-in Cytohubba by different algorithms. (B) P0 and P60 ... fluid retention in knee area
Molecular basis of AR and STK11 genes associated ... - SpringerOpen
WebHere, the common algorithms (MCC, MNC, EPC, Degree, Closeness, Stress, and Radiality) were used to explore the key genes (Su et al., 2024). Subsequently, the GO and KEGG enrichment analysis was ... WebDec 3, 2024 · The gene network was analyzed using 12 scoring methods available in Cytohubba - betweenness, bottleneck, closeness, clustering coefficient (CC), degree, density of maximum neighborhood component (DMNC), eccentricity (EcC), edge percolated component (EPC), maximal clique centrality (MCC), maximum neighborhood component … WebOct 27, 2024 · The STRING database (v.11.5) was used to establish PPIs between genes in the WGCNA module with a confidence level of 0.4, and the interaction network was visualized using Cytoscape. The hub genes of the WGCNA module were screened with the Closeness, Stress, and Radiality algorithms of the cytoHubba plugin in Cytoscape. fluid retention with chf